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elongin A2; RNA polymerase 2 transcription factor SIII subunit A2 (EloA2, TCEB3B, TCEB3L)
Function:
- component of elongin
- subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the elongin BC complex
Structure:
- the elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV]
- contains 1 TFIIS N-terminal domain
Compartment: nucleus (probable)
Expression: specifically expressed in testis
General
elongin A (EloA)
Properties
SIZE: entity length = 753 aa
MW = 84 kD
COMPARTMENT: cell nucleus
MOTIF: TFIIS N-terminal {5-80}
Activation domain {500-659}
MOTIF: Elongin BC interaction {528-537}
Database Correlations
UniProt Q8IYF1
PFAM correlations
Entrez Gene 51224
Kegg hsa:5122
References
UniProt :accession Q8IYF1