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elongin A1; elongin 110 kD subunit; transcription elongation factor B polypeptide 3; RNA polymerase II transcription factor SIII subunit A1; SIII p110 (EloA1, TCEB3, MSTP059)
Function:
- component of elongin
- C subunit mediates the binding of the elongin BC complex to subunit A (putative)
Structure:
- elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV]
- contains 1 F-box domain
- contains 1 TFIIS N-terminal domain
Compartment: nucleus (probable)
General
elongin A (EloA)
phosphoprotein
Properties
SIZE: entity length = 772 aa
MW = 87 kD
COMPARTMENT: cell nucleus
MOTIF: TFIIS N-terminal {4-79}
Ser phosphorylation site {S125}
Ser phosphorylation site {S137}
Activation domain {522-681}
MOTIF: Elongin BC interaction {550-559}
F-box domain {566-610}
Database Correlations
OMIM 600786
UniProt Q14241
PFAM correlations
Entrez Gene 6924
Kegg hsa:6924
References
- UniProt :accession Q14241
- OMIM :accession 600786