Contents

Search

elongin (SIII, transcription elongation factor B, TEFB)

Function: - general transcription elongation factor that increases RNA polymerase 2 transcription elongation past template- encoded arresting sites Structure: - heterotrimer of an A (A1, A2 or A3), B & C subunit regulatory subunits B & C (elongin BC complex)

Related

elongin BC complex positive transcription elongation factor B (P-TEFB, CDK9/cyclin T complex)

General

multisubunit protein transcription elongation factor

Properties

COMPARTMENT: cell nucleus SUBUNITS: elongin A elongin B MOTIF: Ubiquitin-like {1-66} acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl elongin C

Database Correlations

OMIM 600786

References

  1. OMIM :accession 600786
  2. UniProt :accession Q14241 UniProt :accession Q8IYF1

Components

elongin A (EloA) elongin B; elongin 18 kD subunit; transcription elongation factor B polypeptide 2; RNA polymerase II transcription factor SIII subunit B; SIII p18TCEB2 (EloB, TCEB2) elongin C; elongin 15 kD subunit; transcription elongation factor B polypeptide 1; RNA polymerase II transcription factor SIII subunit C; SIII p15TCEB1 (EloC, TCEB1)