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elongation of very long chain fatty acids protein 1 (ELOVL1, SSC1, CGI-88)
Function:
- role in tissue-specific synthesis of very long chain fatty acids & sphingolipids
- may catalyze one or both of the reduction reactions in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative
Structure:
- di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins
- belongs to the ELO family
Compartment: edoplasmic reticulum membrane
General
elongation of very long chain fatty acids protein
membrane protein
oxidoreductase
Properties
SIZE: MW = 33 kD
entity length = 279 aa
COMPARTMENT: endoplasmic reticulum
MOTIF: transmembrane domain {23-43}
transmembrane domain {61-81}
transmembrane domain {176-196}
transmembrane domain {201-221}
transmembrane domain {231-251}
Di-lysine motif {275-279}
Database Correlations
UniProt Q9BW60
Pfam PF01151
References
UniProt :accession Q9BW60