Search
elexacaftor
Indications:
- cystic fibrosis with Phe508del allele
General
pulmonary agent
Database Correlations
PUBCHEM cid=134587348
References
- Middleton PG, Mall MA, Drevinek P et al.
Elexacaftor-tezacaftor-ivacaftor for cystic fibrosis with a single
Phe508del allele.
N Engl J Med 2019 Nov 7;
PMID: 31697873
https://www.nejm.org/doi/10.1056/NEJMoa1908639
- Heijerman HGM, McKone EF, Downey EG et al.
Efficacy and safety of the elexacaftor plus tezacaftor plus
ivacaftor combination regimen in people with cystic fibrosis
homozygous for the F508del mutation: A double-blind, randomised,
phase 3 trial.
Lancet 2019 Oct 30
PMID: 31679946
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32597-8/fulltext
Component-of
elexacaftor/ivacaftor/tezacaftor