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EH domain-binding protein 1 (EHBP1, KIAA0903, NACSIN)

Function: - role in actin reorganization (putative) - links clathrin-mediated endocytosis to actin cytoskeleton - interacts with EHD2 Structure: contains 1 CH domain (calponin-homology domain) Compartment: - cytoplasm, membrane - mostly found in cytosol & plasma membrane Alternative splicing: named isoforms=3

General

cytoskeletal protein

Properties

SIZE: MW = 140 kD entity length = 1231 aa COMPARTMENT: cytoplasm MOTIF: coiled coil {185-210} glutamate-rich region {362-365} MOTIF: glutamate residue (SEVERAL) calponin homology domain NAME: calponin homology domain SITE: 443-545 coiled coil {808-879} coiled coil {1076-1100} glutamate-rich region {1110-1113} MOTIF: glutamate residue (SEVERAL) coiled coil {1136-1230}

Database Correlations

UniProt Q8NDI1

References

UniProt :accession Q8NDI1