EGF-like module-containing mucin-like hormone receptor-like 1 (cell surface glycoprotein EMR1, EMR1 hormone receptor, EMR1, TM7LN3)

Function: - role in cell-cell interactions Structure: 1) belongs to the G-protein coupled receptor 2 family, LN-TM7 subfamily 2) contains 6 EGF-like domains - contains 1 GPS domain Compartment: membrane Alternative splicing: named isoforms=2 Wide expression, especially peripheral blood mononuclear cells

General

glycoprotein transmembrane 7 protein

Properties

SIZE: MW = 98 kD entity length = 886 aa COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {21-599} MOTIF: EGF domain {31-316} (6) MOTIF: cysteine residue {C35} MODIFICATION: cysteine residue {C47} cysteine residue {C41} MODIFICATION: cysteine residue {C56} cysteine residue {C47} MODIFICATION: cysteine residue {C35} cysteine residue {C56} MODIFICATION: cysteine residue {C41} cysteine residue {C58} MODIFICATION: cysteine residue {C78} cysteine residue {C78} MODIFICATION: cysteine residue {C58} N-glycosylation site {N189} N-glycosylation site {N232} N-glycosylation site {N312} N-glycosylation site {N448} GPS {547-596} transmembrane domain {600-627} cytoplasmic loop {628-634} transmembrane domain {635-656} exoplasmic loop {657-666} MOTIF: N-glycosylation site {N661} transmembrane domain {667-690} cytoplasmic loop {691-709} transmembrane domain {710-731} exoplasmic loop {732-747} transmembrane domain {748-776} cytoplasmic loop {777-794} transmembrane domain {795-814} exoplasmic loop {815-829} transmembrane domain {830-852} cytoplasmic domain {853-886}

Database Correlations

OMIM 600493 UniProt Q14246 PFAM correlations

References

UniProt :accession Q14246