EGF-like, fibronectin type-3 & laminin G-like domain-containing protein (EGFLAM, AGRINL, AGRNL)

Structure: - contains 3 EGF-like domains - contains 2 fibronectin F3 modules - contains 3 laminin G-like domains Compartment: secreted (putative) Alternative splicing: named isoforms=6

Properties

SIZE: entity length = 1017 aa MW = 111 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-24} fibronectin type III domain or F3 module {34-133} MOTIF: N-glycosylation site {N47} fibronectin type III domain or F3 module {141-237} EGF domain {343-381} MOTIF: cysteine residue {C347} MODIFICATION: cysteine residue {C358} cysteine residue {C352} MODIFICATION: cysteine residue {C369} cysteine residue {C358} MODIFICATION: cysteine residue {C347} cysteine residue {C369} MODIFICATION: cysteine residue {C352} cysteine residue {C371} MODIFICATION: cysteine residue {C380} cysteine residue {C380} MODIFICATION: cysteine residue {C371} Laminin G-like 1 {386-564} MOTIF: cysteine residue {C534} MODIFICATION: cysteine residue {C564} cysteine residue {C564} MODIFICATION: cysteine residue {C534} EGF domain {565-602} MOTIF: cysteine residue {C569} MODIFICATION: cysteine residue {C580} cysteine residue {C574} MODIFICATION: cysteine residue {C590} cysteine residue {C580} MODIFICATION: cysteine residue {C569} cysteine residue {C590} MODIFICATION: cysteine residue {C574} cysteine residue {C592} MODIFICATION: cysteine residue {C601} cysteine residue {C601} MODIFICATION: cysteine residue {C592} Laminin G-like 2 {609-788} EGF domain {784-820} MOTIF: cysteine residue {C788} MODIFICATION: cysteine residue {C799} cysteine residue {C793} MODIFICATION: cysteine residue {C808} cysteine residue {C799} MODIFICATION: cysteine residue {C788} cysteine residue {C808} MODIFICATION: cysteine residue {C793} cysteine residue {C810} MODIFICATION: cysteine residue {C819} cysteine residue {C819} MODIFICATION: cysteine residue {C810} Laminin G-like 3 {835-1014} MOTIF: cysteine residue {C987} MODIFICATION: cysteine residue {C1014} cysteine residue {C1014} MODIFICATION: cysteine residue {C987}

Database Correlations

UniProt Q63HQ2 PFAM correlations

References

UniProt :accession Q63HQ2