EGFR-coamplified & overexpressed protein; ECop; glioblastoma-amplified secreted protein; NF-kappa-B-activating protein 055N (ECOP, GASP, VOPP1)

Function: - increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding & associated apoptotic response, when overexpressed Structure: belongs to the ECOP family Compartment: - nucleus, membrane - when overexpressed, localizes in the nucleus & perinuclear regions

General

membrane protein nuclear protein

Properties

SIZE: entity length = 172 aa MW = 19 kD COMPARTMENT: cell nucleus MOTIF: signal sequence {1-22} transmembrane domain {61-81} proline-rich region SITE: 87-164 MOTIF: proline residue (SEVERAL)

Database Correlations

UniProt Q96AW1 KEGG correlations

References

UniProt :accession Q96AW1