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ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7, lysosomal apyrase-like protein 1, ENTPD7, LALP1)
Function:
- preferentially hydrolyzes nucleoside 5'-triphosphates order of activity with respect to possible substrates is UTP > GTP > CTP
Cofactor: Ca+2
Structure: belongs to the GDA1/CD39 NTPase family
Compartment:
- membrane
- localizes to intracellular vesicular compartments
General
ectonucleoside triphosphate diphosphohydrolase
glycoprotein
transmembrane 2 protein
Properties
SIZE: MW = 69 kD
entity length = 604 aa
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-28}
transmembrane domain {29-49}
exoplasmic loop {50-546}
MOTIF: N-glycosylation site {N330}
transmembrane domain {547-567}
cytoplasmic domain {568-604}
Database Correlations
UniProt Q9NQZ7
Pfam PF01150
References
UniProt :accession Q9NQZ7