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transcription factor COE4; early B-cell factor 4; EBF-4; olf-1/EBF-like 4; O/E-4; OE-4 (EBF4, COE4, KIAA1442)
Function:
- transcriptional factor
- recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (putative)
- forms either a homodimer or a heterodimer with a related family member (putative)
Structure:
- belongs to the COE family
- contains 1 IPT/TIG domain
Compartment: nucleus (putative)
Alternative splicing: named isoforms=2
General
COE family transcription factor
Properties
SIZE: entity length = 602 aa
MW = 64 kD
COMPARTMENT: cell nucleus
MOTIF: DNA interaction {64-67}
Zinc finger
NAME: Zinc finger
SITE: 152-171
EFFECTOR-BOUND: Zn+2
MOTIF: arginine residue {164}
asparagine residue {173}
DNA interaction {198-205}
DNA interaction {237-240}
IPT/TIG {256-338}
Database Correlations
OMIM 609935
UniProt Q9BQW3
Pfam PF01833
Entrez Gene 57593
Kegg hsa:57593
References
UniProt :accession Q9BQW3