probable E3 ubiquitin-protein ligase KIAA0614 (KIAA0614, HECTD4)

Function: - E3 ubiquitin-protein ligase - protein modification; protein ubiquitination Structure: - contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain - contains 2 LRR repeats (leucine-rich repeats) Alternative splicing: named isoforms=2

General

enzyme leucine-rich repeat-containing protein (LRRC) E3 ubiquitin ligase; ubiquitin-ligating enzyme E3; N end-recognizing protein

Properties

SIZE: entity length = 3000 aa MW = 328 kD MOTIF: leucine-rich repeat SITE: 7-30 MOTIF: leucine residue (SEVERAL) serine-rich region {181-184} MOTIF: serine residue (SEVERAL) serine-rich region {311-314} MOTIF: serine residue (SEVERAL) alanine-rich region {592-595} MOTIF: alanine residue (SEVERAL) proline-rich region SITE: 929-933 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 1085-1088 MOTIF: proline residue (SEVERAL) leucine-rich repeat SITE: 1479-1504 MOTIF: leucine residue (SEVERAL) serine-rich region {1871-1913} MOTIF: serine residue (SEVERAL) HECT domain {2631-3000} MOTIF: cysteine residue {C2968}

Database Correlations

UniProt Q9Y4D8 Pfam PF00632

References

UniProt :accession Q9Y4D8