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E2F site

Origionally identified as promoter element in Adenovirus early gene E1a. Presumbably different from SRF site.

General

promoter element

Properties

MISC-INFO: consensus

References

  1. Mudryj M, Hiebert SW, Nevins JR. A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J. 1990 Jul;9(7):2179-84. PMID: 2141565
  2. Weintraub SJ, Prater CA, Dean DC. Retinoblastoma protein switches the E2F site from positive to negative element. Nature. 1992 Jul 16;358(6383):259-61. PMID: 1321348