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dystrophin-related protein 2 (DRP2)
Function:
- possibly involved in membrane-cytoskeleton interactions of the central nervous system
Structure:
- contains 2 spectrin repeats
- contains 1 WW domain
- contains 1 ZZ-type Zn+2 finger
Compartment: cytoplasm, cytoskeleton (probable)
Expression:
- brain & spinal cord; very low levels in eye, ovary, epididymis & testis; not in cardiac & skeletal muscle
General
cytoskeletal protein
phosphoprotein
zinc finger protein
Properties
SIZE: entity length = 957 aa
MW = 108 kD
COMPARTMENT: cytoplasm
MOTIF: spectrin repeat {102-179}
spectrin repeat {231-337}
WW domain (W/rsp5/WWP domain) {358-383}
Zn finger ZZ-type
NAME: Zn finger ZZ-type
SITE: 604-651
EFFECTOR-BOUND: Zn+2
Thr phosphorylation site {T910}
Database Correlations
OMIM 300052
UniProt Q13474
PFAM correlations
Entrez Gene 1821
Kegg hsa:1821
References
- UniProt :accession Q13474
- Entrez Gene :accession 1821