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drug interaction(s) of methotrexate with influenza virus vaccine

Drug interactions: - methotrexate may diminish response to influenza virus vaccine - hold methotrexate for 1 week after influenza virus vaccine [1]

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DRUGS: methotrexate influenza virus vaccine

References

  1. Park JK et al. A multicenter, prospective, randomized, parallel-group trial on the effects of temporary methotrexate discontinuation for one week versus two weeks on seasonal influenza vaccination in patients with rheumatoid arthritis. Arthritis Rheumatol 2023 Feb; 75:171. PMID: 35930728 https://onlinelibrary.wiley.com/doi/10.1002/art.42318