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drug interaction(s) of haloperidol with rivastigmine

Drug interactions: - increased mortality when rivastigmine is co-administered with haloperidol for treatment of delirium in the ICU

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DRUGS: haloperidol rivastigmine

References

  1. van Eijk MM, Roes KC, Honing ML et al Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial. Lancet. 2010 Nov 27;376(9755):1829-37. PMID: 21056464