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drug interaction(s) of methadone in combination with benzodiazepines

Drug interactions: - methadone in combination with benzodiazepine increases risk of death due to opioid overdose [1]

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DRUGS: methadone benzodiazepine

References

  1. Centers for Disease Control and Prevention (CDC) Vital Signs: Risk for Overdose from Methadone Used for Pain Relief - United States, 1999-2010 MMWR. July 6, 2012 / 61(26);493-497 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6126a5.htm