Contents

Search

drug interaction(s) of ondanstetron with SSRIs

Drug interactions: - increase of QTc interval & risk of Torsade de Pointes - ondansetron is associated with QTc prolongation as are several SSRIs (see drug-induced prolongation of the QT interval)

Properties

DRUGS: ondansetron serotonin reuptake inhibitor

References

  1. Castro VM et al. QT interval and antidepressant use: A cross sectional study of electronic health records. BMJ 2013 Jan 29; 346:f288. PMID: 23360890
  2. FDA MedWatch Zofran (ondansetron): Drug Safety Communication - Risk of Abnormal Heart Rhythms http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm272041.htm - Ondansetron (Zofran) IV: Drug Safety Communication - QT prolongation http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm310219.htm