Search
drug interaction(s) of triptans with SSRIs
Drug interactions:
- triptans in combination with SSRI probably do not increase risk of serotonin syndrome, although caution & vigilence is recommended [1]
- serotonin syndrome is rare is patients prescribed combination of triptan with SSRI or SNRI [2]
Properties
DRUGS: serotonin agonist
serotonin reuptake inhibitor
References
- Paauw DS
Dangerous and Deadly Drug Combinations
Medscape. June 30, 2016
http://www.medscape.com/features/slideshow/dangerous-drug-combinations
- Orlova Y, Rizzoli P, Loder E
Association of Coprescription of Triptan Antimigraine Drugs
and Selective Serotonin Reuptake Inhibitor or Selective
Norepinephrine Reuptake Inhibitor Antidepressants With
Serotonin Syndrome.
JAMA Neurol. Published online February 26, 2018
PMID: 29482205
https://jamanetwork.com/journals/jamaneurology/fullarticle/2673391