drug interaction(s) of calcium channel blockers with erythromycin

Drug interactions: - erythromycin, a potent inhibitor of cyt P450 3A4 can significantly increase plasma levels of calcium channel blockers - older patients may end up in hospital with hypotension or shock - reports of edema, arrythmias or heart block

Properties

DRUGS: calcium channel blocker erythromycin

References

- Prescriber's Letter 18(3): 2011 COMMENTARY: Calcium Channel Blocker-Macrolide Interaction Detail-Document#: 270307 (subscription needed) http://www.prescribersletter.com