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drug interaction(s) of statins with influenza virus vaccines

Drug interactions: - titers to various influenza strains are up to 2/3 lower in elderly taking statins versus those not taking them - lower vaccine effectiveness against such acute illnesses by ~10-20% among those on statins

Properties

DRUGS: HMG CoA reductase inhibitor influenza virus vaccine

References

  1. Elia J, Sadoughi S, Saitz R Statins Seem to Reduce Efficacy of Flu Vaccines Physician's First Watch, Oct 29, 2015 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org - Black S, Nicolay U, Del Giudice G, Rappuoli R. Influence of Statins on Influenza Vaccine Response in Elderly Individuals. J Infect Dis. 2015 Oct 28. pii: jiv456. [Epub ahead of print] PMID: 26516142