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drug interaction(s) of sulfonylureas with warfarin

Drug interactions: - increased risk for hypoglycemia among patients concurrently receiving warfarin & glipizide or glimepiride (RR=1.2 relative to sulfonylurea alone) - risk is higher in the elderly

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DRUGS: sulfonylurea warfarin

References

  1. Romley JA, Gong C, Jena AB Association between use of warfarin with common sulfonylureas and serious hypoglycemic events: retrospective cohort analysis. BMJ. 2015 Dec 7;351:h6223. PMID: 26643108