drug interaction(s) of trimethoprim/sulfamethoxazole with warfarin

Drug interactions: - warfarin effect can be INCREASED with: - trimethoprim/sulfamethoxazole - significantly increased risk of bleeding in elderly

Properties

DRUGS: trimethoprim/sulfamethoxazole warfarin

References

- Fischer HD et al Hemorrhage During Warfarin Therapy Associated With Cotrimoxazole and Other Urinary Tract Anti-infective Agents Arch Intern Med. 2010;170(7):617-621 PMID: 20386005 http://archinte.ama-assn.org/cgi/content/abstract/170/7/617