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drug interaction(s) of palbociclib with proton pump inhibitors
Drug interactions:
- concurrent use of proton pump inhibitor with palbociclib is associated with a shorter survival [1]
- 2-year overall survival 69.5% vs 89.3% [1]
Properties
DRUGS: palbociclib
proton pump inhibitor
References
- Bassett M
PPIs Linked to Worse Outcomes With Widely Used Breast Cancer Drug.
Concomitant use of proton pump inhibitors with palbociclib associated with
shorter survival.
MedPage Today July 21, 2023
https://www.medpagetoday.com/hematologyoncology/breastcancer/105604
- Lee JE, Kwon SH, Kwon S et al
Concomitant Use of Proton Pump Inhibitors and Palbociclib Among Patients
With Breast Cancer.
JAMA Netw Open. 2023;6(7):e2324852
PMID: 37477917 PMCID: PMC10362477 Free PMC article
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807485