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drug interaction(s) of bisphosphonates with proton pump inhibitors

Drug interactions: - proton pump inhibitors may blunt the beneficial effect of bisphosphonates to prevent hip fractures in the elderly (> 70 years of age) [1]

Properties

DRUGS: bisphosphonate proton pump inhibitor

References

  1. Abrahamsen B et al Proton pump inhibitor use and the antifracture efficacy of alendronate. Arch Intern Med 2011 Jun 13; 171:998. PMID: 21321287