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drug interaction(s) of salicylates with sulfonylureas

Drug interactions: - salicylates appear to have glucose-lowering properties via unknown mechanism(s). Additionally, salicylates may cause displacement of protein-binding of some sulfonylureas - decreased renal clearance of sulfonylureas may also occur

Properties

DRUGS: salicylate sulfonylurea

References

  1. Cherner R et al Prolonged tolbutamide-induced hypoglycemia. JAMA 1963; 185:883
  2. Anonymous Drug Interaction Br Med J 1971; 1:389