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drug interaction(s) of pregabalin with opiates
Drug interactions:
- combination increases risk of opioid overdose mortality
Properties
DRUGS: pregabalin
opioid agonist
References
- Gomes T, Greaves S, van den Brink W et al
Pregabalin and the Risk for Opioid-Related Death: A Nested
Case-Control Study.
Ann Intern Med. Aug 21, 2018
PMID: 30140853
http://annals.org/aim/article-abstract/2697572/pregabalin-risk-opioid-related-death-nested-case-control-study
- Throckmorton DC, Woodcock J
Combined Gabapentinoid and Opioid Use: The Consequences of
Shifting Prescribing Trends.
Ann Intern Med. Aug 21, 2018
PMID: 30140901
http://annals.org/aim/article-abstract/2698046/combined-gabapentinoid-opioid-use-consequences-shifting-prescribing-trends
- Bykov K, Bateman BT, Franklin JM, Vine SM, Patorno E.
Association of gabapentinoids with the risk of opioid-related adverse
events in surgical patients in the United States.
JAMA Netw Open 2020 Dec 29; 3:e2031647
PMID: 33372975 PMCID: PMC7772715 Free PMC article
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2774489