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drug interaction(s) of tofacitinib with shingles vaccine

Drug interactions: - tofacitinib may interefere with immunological response to the shingles vaccine [1] - start tofacitinib 2 weeks after shingles vaccination

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DRUGS: tofacitinib Herpes zoster vaccine

References

  1. Winthrop KL, Wouters AG, Choy EH et al. The safety and immunogenicity of live zoster vaccination in patients with rheumatoid arthritis before starting tofacitinib: A randomized phase II trial. Arthritis Rheumatol 2017 Oct; 69:1969 PMID: 28845577 - Winthrop KL, Curtis JR, Lindsey S et al Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy. Arthritis Rheumatol. 2017 Oct;69(10):1960-1968. PMID: 28845604