Contents

Search

drug adverse effects of antiplatelet agents

Adverse effects: - increased risk of bleeding - especially risk of upper GI bleed - risk of upper GI bleed attenuated if used in combination with proton pump inhibitor - with chronic kidney disease - lack of clear efficacy in reducing cardiovascular morbidity & mortality - increased risk of bleeding [2]

Properties

DRUGS: antiplatelet agent FORM: drug adverse effects antiplatelet agent

References

  1. Ibanez L, Vidal X, Vendrell L, Moretti U, Laporte JR; Spanish- Italian Collaborative Group for the Epidemiology of Gastrointestinal Bleeding. Upper gastrointestinal bleeding associated with antiplatelet drugs. Aliment Pharmacol Ther. 2006 Jan 15;23(2):235-42. PMID: 16393302
  2. Palmer SC Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis Ann Intern Med March 20, 2012 156:445-459 PMID: 22431677