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drug adverse effects of androgens
Adverse effects:
- use of products that contain synthetic anabolic steroids is associated with risk for hepatotoxicity
- excessive muscle bulk
- acne
- gynecomastia
- decreased testicular volume (small testicles)
- exogenous testosterone may result in irreversible decline in spermatogenesis, infertility & permanent inability to produce endogenous testosterone [2]
- long-term use of anabolic androgenic steroids may be linked to diminished MRI brain volume, including less overall gray matter, lower cerebral cortex & putamen volumes, & thinner cerbral cortex throughout the brain. [3]
- high-dose androgen abuse [4]
- myocardial infarction
- heart failure
- stroke
- depression
- hostility, aggression
- hepatotoxicity
- male infertility [4]
Properties
DRUGS: androgen
FORM: drug adverse effects androgen
References
- FDA News Release. April 13, 2015
FDA warns consumers not to use muscle growth product called
Tri-Methyl Xtreme
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm442494.htm
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
- Bjornebekk A et al.
Structural brain imaging of long term anabolic-androgenic
steroid users and non-using weightlifters.
Biol Psychiatry 2016 Jun 30;
PMID: 27616036
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(16)32529-X/abstract
- Brooks M
FDA Adds New Warnings to All Testosterone Product Labels.
Medscape. Oct 25, 2016
http://www.medscape.com/viewarticle/870932
- FDA Safety Alert. Oct 25, 2016
Testosterone and Other Anabolic Androgenic Steroids (AAS):
FDA Statement - Risks Associated With Abuse and Dependence.
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm526151.htm