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drug adverse effects of antiretroviral protease inhibitors

Adverse effects: 1) hyperlipidemia: a) increased cholesterol & triglycerides b) protease inhibitor lipodystrophy syndrome c) increased risk of myocardial infarction [4] 2) hyperglycemia 3) osteoporosis 4) hyperprolactinemia [3]

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DRUGS: antiretroviral protease inhibitor FORM: drug adverse effects antiretroviral protease inhibitor

References

  1. Prescriber's Letter 7(8):45 2000
  2. Prescriber's Letter 9(8):47 2002
  3. Medical Knowledge Self Assessment Program (MKSAP) 14, American College of Physicians, Philadelphia 2006
  4. Lang S et al, Impact of Individual Antiretroviral Drugs on the Risk of Myocardial Infarction in Human Immunodeficiency Virus-Infected Patients A Case-Control Study Nested Within the French Hospital Database on HIV ANRS Cohort CO4 Arch Intern Med. 2010;170(14):1228-1238 PMID: 20660842 http://archinte.ama-assn.org/cgi/content/short/170/14/1228