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drug adverse effects of lipophilic statins

Adverse effects: - discontinuation of lipophilic statin* increases risk of Parkinson's disease [1] - acute memory impairment within 30 days (RR=4.4, all antihyperlipidemic agents) [2] * lipophilic statins cross the blood brain barrier

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DRUGS: LIPHOPHILIC-STATIN FORM: drug adverse effects liphophilic statin

References

  1. Physician's First Watch, July 25, 2013 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org - Lee Y-C et al. Discontinuation of statin therapy associates with Parkinson disease: A population PMID: 23884037 http://neurology.org/content/early/2013/07/24/WNL.0b013e31829d873c
  2. Strom BL et al Statin Therapy and Risk of Acute Memory Impairment. JAMA Intern Med. Published online June 08, 2015 http://archinte.jamanetwork.com/article.aspx?articleID=2301148