protein ripply3; Down syndrome critical region protein 6 (DSCR6, RIPPLY3)

Structure: - the ripply homology domain is required for transcriptional repression (putative) - the WRPW motif is required for binding to tle/groucho proteins (putative) - belongs to the ripply family Compartment: nucleus (putative) Alternative splicing: named isoforms=2 Expression: - expressed at a low level in fetal kidney & fetal brain

General

Down syndrome critical region protein nuclear protein

Properties

SIZE: entity length = 190 aa MW = 20 kD COMPARTMENT: cell nucleus MOTIF: WRPW {39-42} Ripply homology {77-112}

Database Correlations

OMIM 609892 UniProt P57055 Entrez Gene 53820 Kegg hsa:53820

References

UniProt :accession P57055