doublesex- & mab-3-related transcription factor 1 (DM domain expressed in testis protein 1, DMRT1, DMT1)

Function: - may be required for testis development Structure: - contains 1 DM DNA-binding domain Compartment: nucleus Expression: - testis specific - expressed in the genital ridges of 6-week-old male embryos - becomes confined to the forming seminiferous tubules (possibly Sertoli cells) at 7 weeks - not detected in female embryos

General

doublesex- & mab-3-related transcription factor (DMRT) testis-specific protein

Properties

SIZE: MW = 39 kD entity length = 373 aa COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 72-118 serine-rich region {322-347} MOTIF: serine residue (SEVERAL)

Database Correlations

OMIM 602424 UniProt Q9Y5R6 Pfam PF00751

References

UniProt :accession Q9Y5R6