dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3A; oligosaccharyl transferase subunit STT3A; STT3-A; B5; integral membrane protein 1 (TMC, STT3A, ITM1)

Function: - component of N-oligosaccharyl transferase Compartment: endoplasmic reticulum membrane Expression: - expressed in placenta, liver, muscle, pancreas > brain, lung, & kidney - expressed in skin fibroblasts

General

glycoprotein protein subunit transmembrane 10 protein

Properties

SIZE: MW = 80 kD entity length = 705 aa COMPARTMENT: endoplasmic reticulum MOTIF: cytoplasmic domain {1-17} transmembrane domain {18-38} exoplasmic loop {39-114} transmembrane domain {115-135} cytoplasmic loop {136-169} transmembrane domain {170-190} exoplasmic loop {191-208} transmembrane domain {209-229} cytoplasmic loop {230-235} transmembrane domain {236-259} exoplasmic loop {260-300} transmembrane domain {301-321} cytoplasmic loop {322-359} transmembrane domain {360-380} exoplasmic loop {381-383} transmembrane domain {384-404} cytoplasmic loop {405-405} transmembrane domain {406-426} exoplasmic loop {427-453} transmembrane domain {454-474} cytoplasmic domain {475-705} MOTIF: N-glycosylation site {N537} N-glycosylation site {N544} N-glycosylation site {N548}

Database Correlations

OMIM 601134 UniProt P46977 Pfam PF02516 Kegg hsa:3703 ENZYME 2.4.1.119

References

UniProt :accession P46977