Search
DNA-binding protein SATB1; special AT-rich sequence-binding protein 1 (SATB1)
Function:
- binds to DNA at special AT-rich sequences at nuclear matrix or scaffold-associated regions
- thought to recognize the sugar-phosphate structure of double-stranded DNA
- sumoylated
Structure:
- belongs to the CUT homeobox family
- contains 2 CUT DNA-binding domains
- contains 1 homeobox DNA-binding domain
Compartment: nucleus
Expression: expressed predominantly in thymus
General
DNA-binding protein
Properties
SIZE: entity length = 763 aa
MW = 86 kD
COMPARTMENT: cell nucleus
MOTIF: DNA-binding motif
SITE: 361-448
DNA-binding motif
SITE: 484-571
glutamine-rich region {591-607}
MOTIF: glutamine residue (SEVERAL)
proline-rich region
SITE: 609-614
MOTIF: proline residue (SEVERAL)
homeodomain
SITE: 645-704
Database Correlations
OMIM 602075
UniProt Q01826
PFAM correlations
Entrez Gene 6304
Kegg hsa:6304
References
UniProt :accession Q01826