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drosophila discs large [dlg] gene
Mutations in dlg (discs large gene) lead to a loss of tight (septate) junctions between epithelial cells & aberrant proliferation of cells in the imaginal disk.
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drosophila discs large [dlg] protein
General
invertebrate-specific gene
tumor suppressor gene or anti-oncogene
Properties
ORGANISM: Drosophila
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: drosophila discs large [dlg] protein
COMPARTMENT: cell nucleus
CELL: unspecified cell type
ORGANISM: Drosophila
MOTIF: transcriptional termination site
transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
References
- Pawson T
Protein modules and signalling networks
Nature 373:573 1995
PMID: 7531822