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diffuse cutaneous (pseudoxanthomatous) mastocytosis (DCM)
A generalized cutaneous mastocytosis.
Clinical manifestations:
1) yellowish, thickened appearance of skin
2) lesions smooth with scattered areas of elevation, resembling leather
3) exaggerated skin folds, especially in axilla & groin
4) large bullae may occur spontaneously or following trauma
5) may present as erythroderma
Differential diagnosis:
1) Histiocytosis
2) secondary syphilis
3) sarcoid
4) histiocytoma
5) non-X histiocytosis
General
mastocytosis
References
Color Atlas & Synopsis of Clinical Dermatology, Common
& Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY,
1997, pg 718, 562-65