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desiccated thyroid (Armour, Niva, Apur)

ground up pork thyroid gland Dosage: - contains BOTH levothyroxine (T4) & liothyronine (T3) - 38 ug levothyroxine (T4) & 9 ug liothyronine (T3) per grain of thyroid - Niva thyroid 15, 30, 60, 90, 120, 180, 240, 300 mg - Apur thyroid 15, 30, 60, 90, 120 mg - Adthyza thyroid 15, 30, 60, 90, 120 mg Pharmacokinetics: - the T4/T3 ratio is 14 compared with 4 in pigs [2] - serum T4 tends to be low & serum T3 tends to be high relative to normal patients not receiving thyroid hormone replacement [2] - thyroxine alone results in serum T4/T3 ratio indistinguishable from those of normal people without thyroid disease [2]

Related

thyroxine/triiodothyronine (Euthroid, Thyrolar)

General

pharmacologic combination thyroid agent

References

  1. Prescriber's Letter 15(10): 2008 Desiccated Thyroid vs. Synthetic Thyroid Supplementation Detail-Document#: 241013 (subscription needed) http://www.prescribersletter.com
  2. Frieden J Cliniton's Hypothyroid Medication Draws Interest. MedPage Today. Sept 26, 2016 http://www.medpagetoday.com/Endocrinology/Thyroid/60471