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desloratadine (Clarinex)

Tradename: Clarinex. Indications: - treatment of allergies - seasonal allergic rhinitis, allergic conjunctivitis - atopy, urticaria [2] Dosage: 5 mg PO QD (higher doses NOT more effective) Tabs: 5 mg Pharmacokinetics: -> longer 1/2 life than loratadine Adverse effects: - drowsiness (especially at higher doses) Laboratory: - desloratadine in blood - desloratadine in serum/plasma - desloratadine in urine Mechanism of action: 1) non-sedating antihistamine (H1 receptor antagonist) 2) the major active metabolite of loratadine Notes: Manufacturer: Schering-Plough

Interactions

drug adverse effects of H1 receptor antagonists

General

H1 receptor antagonist (antihistamine)

Properties


Database Correlations

PUBCHEM cid=124087

References

  1. Prescriber's Letter 9(2):S1 2002 Prescriber's Letter 9(2):12 2002
  2. Deprecated Reference

Component-of

desloratadine/pseudoephedrine