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delta-aminolevulinate in 24 hour urine

Indications: 1) diagnosis & management of acute porphyria 2) NOT a sensitive indicator of Pb poisoning Normal range: - urine (24 hour): a) < 4.5 mg/L (< 34 umol/L) b) 1.5-7.5 mg/day (11.4-57.2 umol/day) Increases: see delta-aminolevulinic acid in serum Decreases: see delta-aminolevulinic acid in serum Method: see delta-aminolevulinic acid in body fluid Specimen: -> collect in dark container containing 10 mL of 6 mol/L HCl a) stable refrigerated for 1 week b) specimen can NOT be used for porphobilinogen & porphyrins which need Na2CO3 as a preservative c) some labs prefer NO preservative so that all heme precursors may be analyzed on the same specimen

Related

delta-aminolevulinate; 5-aminolevulinic acid; aminolevulinic acid (ALA) porphobilinogen porphyria

General

delta-aminolevulinic acid urine 24 hour urine

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  2. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  3. Panel of 7 tests Laboratory Test Directory ARUP: 80103