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delphilin (glutamate receptor, ionotropic, delta 2-interacting protein 1, GRID2IP)
Function:
- postsynaptic scaffolding protein at the parallel fiber- Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton & various signaling molecules
- interacts with C-terminus of the glutamate receptor GRID2 via PDZ domain (putative)
Structure:
- contains 1 FH2 (formin homology 2) domain
- contains 2 PDZ domains (DHR domains)
Compartment: cell junction, synapse (putative)
General
receptor
Properties
SIZE: entity length = 1211 aa
MW = 132 kD
MOTIF: PDZ domain
NAME: PDZ domain
SITE: 3-84
PDZ domain
NAME: PDZ domain
SITE: 279-356
proline-rich region
SITE: 581-662
MOTIF: proline residue (SEVERAL)
proline-rich region
SITE: 750-812
MOTIF: proline residue (SEVERAL)
FH2 {821-1188}
Database Correlations
UniProt A4D2P6
PFAM correlations
Kegg hsa:6419
References
UniProt :accession A4D2P6