dehydrogenase/reductase SDR family (DHRS)

Family of short-chain dehydrogenases/reductases

Specific

dehydrogenase/reductase SDR family member 1 (DHRS1) dehydrogenase/reductase SDR family member 10; 17-beta-hydroxysteroid dehydrogenase DHRS10; retinal short-chain dehydrogenase/reductase retSDR3 (DHRS10, SDR3, HSD17B14, UNQ502/PRO474) dehydrogenase/reductase SDR family member 11 (DHRS11) dehydrogenase/reductase SDR family member 2 (HEP27 protein, protein D, DHRS2) dehydrogenase/reductase SDR family member 4 (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, CR, PHCR, peroxisomal short-chain alcohol dehydrogenase, NADPH-dependent retinol dehydrogenase/reductase, NDRD, SCAD-SRL, humNRDR, PSCD, DHRS4) dehydrogenase/reductase SDR family member 6 (3-hydroxybutyrate dehydrogenase type 2, R-beta-hydroxybutyrate dehydrogenase, oxidoreductase UCPA, BDH2, DHRS6, UNQ6308/PRO20933) dehydrogenase/reductase SDR family member 7 (retinal short-chain dehydrogenase/reductase 4, retSDR4, DHRS7, RETSDR4, CGI-86, UNQ285/PRO3448) dehydrogenase/reductase SDR family member 7C (DHRS7C) dehydrogenase/reductase SDR family member 8 (17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17-beta- HSD XI, 17betaHSDXI, 17bHSD11, 17betaHSD11, retinal short-chain dehydrogenase/reductase 2, retSDR2, cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL tumor antigen HD-CL-03, DHRS8, HSD17B11, PAN1B, PSEC0029, UNQ207/PRO233) dehydrogenase/reductase SDR family member 9 (3-alpha hydroxysteroid dehydrogenase, 3alpha-HSD, RDH-E2, short-chain dehydrogenase/reductase retSDR8, NADP-dependent retinol dehydrogenase/reductase, RDHL, DHRS9) dehydrogenase/reductase SDR family member on chromosome X (DHRSXY, DHRSX, CXorf11, DHRS5X, UNQ6508/PRO21433)

Properties

SIZE: MW = 28 kD entity length = 270 aa COMPARTMENT: cytoplasm MOTIF: binding site SITE: 141-141 FOR-BINDING-OF: Substrate tyrosine residue {Y154} binding site SITE: 158-158 FOR-BINDING-OF: NAD