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dehydrodolichyl diphosphate synthase (Dedol-PP synthase, DHDDS, HDS)
Function:
1) glycosylation pathway
2) catalyzes cis-prenyl chain elongation to produce polyprenyl backbone of dolichol
Structure:
- belongs to the UPP synthetase family
Alternative splicing: named isoforms=3
Expression:
- expressed in testis & kidneys > heart, spleen, thymus
General
enzyme
Properties
SIZE: MW = 39 kD
entity length = 333 aa
MOTIF: active site
Database Correlations
OMIM 608172
UniProt Q86SQ9
References
UniProt :accession Q86SQ9