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deafferentation pain
Pain due to loss of sensory input into the central nervous system
Etiology:
1) lesions in peripheral nervous system
a) avulsion of the brachial plexus
b) peripheral nerve injury
c) trigeminal neuropathy
2) lesions in the CNS
a) thalamic pain
b) brainstem infarction with bulbar pain
Pathology:
1) interruption of afferent nerve impulses (complete or partial)
2) lesions that interrupt the spinothalamic pathways at any level of the nervous system
Clinical manifestations:
1) varying degrees of sensory loss
- disturbances in pain & temperature sensation
2) allodynia
3) hyperalgesia
4) dysesthesias
5) hyperpathia
Laboratory: see specific etiology
Special laboratory:
- nerve conduction study (depending upon etiology)
Radiology:
- magnetic resonance imaging (depending upon etiology)
Management:
1) see chronic pain & neuropathic pain
2) motor mortex stimulation for intractable pain [1]
General
pain [odyn-]
References
- Osenbach RK
Motor Cortex Stimulation for Intractable Pain: Central and
Deafferentation Pain
Medscape Today
http://www.medscape.com/viewarticle/554867_2