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DDD core complex
Function:
- recruits a UBE2E enzyme, such as UBE2E1, UBE2E2 UBE2E3, to form specific DDD-E2 complexes
Structure:
- subunits: composed of at least DET1, DDA1 & DDB1
General
molecular complex
Properties
SUBUNITS: DET1 homolog
COMPARTMENT: cell nucleus
DET1- & DDB1-associated protein 1
FORM: DET1- & DDB1-associated protein 1
DNA damage-binding protein 1
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: CDT1 interaction {1-768}
MOTIF: Thr phosphorylation site {T8}
CUL4A interaction {391-709}
Ser phosphorylation site {S757}
Ser phosphorylation site {S766}
CDT1/CUL4A interaction {771-1140}
References
UniProt :accession O75081
Components
DET1 homolog (De-etiolated-1 homolog, DET1)
DET1- & DDB1-associated protein 1 (placenta cross-immune reaction antigen 1, PCIA-1, DDA1, C19orf58, PCIA1)
DNA damage-binding protein 1; damage-specific DNA-binding protein 1; UV-damaged DNA-binding factor; DDB p127 subunit; DNA damage-binding protein a; DDBa; UV-damaged DNA-binding protein 1; UV-DDB 1; Xeroderma pigmentosum group E-complementing protein; XPCe; XPE-binding factor; XPE-BF; HBV X-associated protein 1; XAP-1 (DDB1, XAP1)