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DBIRD complex
Function:
- acts at the interface between core mRNP particles & RNA polymerase 2& integrates transcript elongation with regulation of alternative splicing
- affects local transcript elongation rates & alternative splicing of a large set of exons embedded in AT-rich DNA regions
Structure:
- subunits include: CCAR2
General
molecular complex
Properties
SUBUNITS: cell cycle & apoptosis regulator protein 2
COMPARTMENT: cell nucleus
MOTIF: Thr phosphorylation site {T35}
Ser phosphorylation site {S124}
Ser phosphorylation site {S675}
Ser phosphorylation site {S678}
Ser phosphorylation site {S681}
coiled coil {829-909}
References
UniProt :accession Q8N163
Components
cell cycle & apoptosis regulator protein 2; cell division cycle & apoptosis regulator protein 2; DBIRD complex subunit KIAA1967; deleted in breast cancer gene 1 protein; DBC-1; DBC.1; p30 DBC (CCAR2, DBC1, KIAA1967)