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c-rel proto-oncogene protein; c-Rel protein (REL)
Function:
- proto-oncogene protein
- may play a role in differentiation & lymphopoiesis
- NF kappa B-related protein
- component of the NF-kappa-B p65-c-Rel complex
- component of the NF-kappa-B p50-c-Rel complex
- component of the NF-kappa-B p52-c-Rel complex
- homodimer; component of the NF-kappa-B c-Rel-c-Rel complex (putative)
- interacts with NKIRAS1
- interacts with NFKBIB (putative)
- interacts with NFKBIE
Structure: contains 1 RHD (Rel-like) domain
Compartment: nucleus (putative)
Interactions
molecular events
Related
c-rel proto-oncogene
General
rel protein family
Properties
COMPARTMENT: cell nucleus
cytoplasm
Database Correlations
OMIM 164910
UniProt Q04864
PFAM correlations
Entrez Gene 5966
Kegg hsa:5966
References
- Molecular Cell Biology (2nd ed) Darnell J; Lodish H
& Baltimore D (eds), Scientific American Books,
WH Freeman, NY 1990, pg 986
- Atlas of genetics & cytogenetics in oncology & haematology
http://atlasgeneticsoncology.org/genes/RELID322.html
- UniProt :accession Q04864
- Entrez Gene :accession 5966
Component-of
molecular complex