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c-rel proto-oncogene protein; c-Rel protein (REL)

Function: - proto-oncogene protein - may play a role in differentiation & lymphopoiesis - NF kappa B-related protein - component of the NF-kappa-B p65-c-Rel complex - component of the NF-kappa-B p50-c-Rel complex - component of the NF-kappa-B p52-c-Rel complex - homodimer; component of the NF-kappa-B c-Rel-c-Rel complex (putative) - interacts with NKIRAS1 - interacts with NFKBIB (putative) - interacts with NFKBIE Structure: contains 1 RHD (Rel-like) domain Compartment: nucleus (putative)

Interactions

molecular events

Related

c-rel proto-oncogene

General

rel protein family

Properties

COMPARTMENT: cell nucleus cytoplasm

Database Correlations

OMIM 164910 UniProt Q04864 PFAM correlations Entrez Gene 5966 Kegg hsa:5966

References

  1. Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 986
  2. Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/RELID322.html
  3. UniProt :accession Q04864
  4. Entrez Gene :accession 5966

Component-of

molecular complex