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cytosolic 5'-nucleotidase 1A (NT5C1A) in serum

Indications: - evaluation of inclusion body myositis Clinical significance: - associated with inclusion body myositis (61%) [2] - also found in patients with systemic lupus erythematosus (14%), systemic sclerosis (23%), dermatomyositis (15%) & healthy individals (5%) [2]

Related

cytosolic 5'-nucleotidase 1A (cN1A, NT5C1A)

General

serology

References

  1. Greenberg SA. Cytoplasmic 5'-nucleotidase autoantibodies in inclusion body myositis: Isotypes and diagnostic utility. Muscle Nerve. 2014 Oct;50(4):488-92. PMID: 24752512
  2. Lloyd TE, Christopher-Stine L, Pinal-Fernandez I et al Cytosolic 5'-Nucleotidase 1A As a Target of Circulating Autoantibodies in Autoimmune Diseases. Arthritis Care Res (Hoboken). 2016 Jan;68(1):66-71. PMID: 25892010 Free PMC Article