cysteine-rich PDZ-binding protein (cysteine-rich interactor of PDZ three, cysteine-rich interactor of PDZ3, CRIPT)

Function: - role in the cytoskeletal anchoring of DLG4 in excitatory synapses (putative) - interacts with TUBB1 - interacts strongly with the PDZ3 domain of members of the DLG4 family - associates with microtubules (putative) - interacts with DLG4 Structure: belongs to the CRIPT family Compartment: - cytoplasm, cell junction, synapse (putative) - cell projection, dendritic spine - colocalizes with DLG4 in asymmetric synapse

Properties

SIZE: entity length = 101 aa MW = 11 kD COMPARTMENT: cytoplasm MOTIF: Sufficient for interaction with DLG4 {95-101} MOTIF: binding site SITE: 98-101 FOR-BINDING-OF: PDZ3

References

UniProt :accession Q9P021